Major histocompatibility complex class I-restricted alloreactive CD4+ T cells
نویسندگان
چکیده
منابع مشابه
Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells
A previous report showed that the proliferative response of helper T cells to class II major histocompatibility complex (MHC)-restricted antigens can be inhibited by analogues of the antigen, which act as T cell receptor (TCR) antagonists. Here we define and analyze peptide variants that antagonize various functions of class I MHC-restricted cytotoxic T lymphocyte (CTL) clones. Of 64 variants a...
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The identity of allogeneic peptide/major histocompatibility complex (MHC) complexes that elicit vigorous T cell responses has remained an interesting problem for both practical and theoretical reasons. Although a few abundant MHC class I-bound peptides have been purified and sequenced, identifying the unique T cell-stimulating peptides from among the thousands of existing peptides is still a ve...
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ژورنال
عنوان ژورنال: Immunology
سال: 2004
ISSN: 0019-2805,1365-2567
DOI: 10.1111/j.1365-2567.2004.01857.x